The 12th Annual European Post Trade AFME Conference is one of the leading events for the European clearing and settlement industry attended by over 200 senior market professionals representing both buy- and sell side, regulatory bodies, central banks and industry service providers. AFME programme is formulated by the AFME Post Trade Board. This year's event covered key issues including the impact of Brexit on European post trade, the regulatory perspectives on CMU, EPTF and CSDR and the developments in distributed ledger technology.